Found 97 of ec50 for PLATELET-DERIVED GROWTH FACTOR RECEPTOR ALPHA
having polymerids = 5778,6175,9666,956 and
complexids = 50000002,50000008
having polymerids = 5778,6175,9666,956 and
complexids = 50000002,50000008
Affinity DataEC50: 0.410nMAssay Description:Inhibition of human PD-1 expressed in rat PBMCs/human PD-L1 expressed in MDA-MB-231 cells protein-protein interaction assessed as increase in PBMCs p...More data for this Ligand-Target Pair
Affinity DataEC50: 0.720nMAssay Description:Inhibition of human PD-1/PD-L1 interactionMore data for this Ligand-Target Pair
Affinity DataEC50: <1nMAssay Description:Inhibition of rat liver Dihydrofolate reductase.More data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Positive allosteric modulation of rat recombinant GABAA alpha6beta3gamma2 receptor expressed in Xenopus laevis oocytes assessed as increase in GABA-i...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 2nMAssay Description:Activation of caspase 3/7 in human 22Rv1 cells by Caspase-Glo reagent based analysisMore data for this Ligand-Target Pair
Ligand Info
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataEC50: 4nMAssay Description:Inhibition of PDGFRalpha by cellular assayMore data for this Ligand-Target Pair
Affinity DataEC50: 4nMAssay Description:Positive allosteric modulation of rat recombinant GABAA gamma2beta3alpha1-beta3alpha6 receptor expressed in Xenopus laevis oocytes assessed as increa...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 8nMAssay Description:Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as increa...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 9nMAssay Description:Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as increa...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 10nMAssay Description:Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as increa...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 10nMAssay Description:Agonist activity at human adrenergic receptor expressed in CHO cellsMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 13nMAssay Description:Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as increa...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 15nMAssay Description:Inhibition of HDAC in human HeLa cells using FLUOR DE LYS-SIRT1 as fluorogenic substrate incubated for 4 hrs by spectrophotometer based analysisMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 23nMAssay Description:Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as increa...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 28nMAssay Description:Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as increa...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 43nMAssay Description:Inhibition of HDAC in human HeLa cells using FLUOR DE LYS-SIRT1 as fluorogenic substrate incubated for 4 hrs by spectrophotometer based analysisMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 44nMAssay Description:Inhibition of HDAC in human HeLa cells using FLUOR DE LYS-SIRT1 as fluorogenic substrate incubated for 4 hrs by spectrophotometer based analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 50nMAssay Description:Inhibition of HDAC in human HeLa cells using FLUOR DE LYS-SIRT1 as fluorogenic substrate incubated for 4 hrs by spectrophotometer based analysisMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 50nMAssay Description:Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as increa...More data for this Ligand-Target Pair
Ligand Info
TargetPlatelet-derived growth factor receptor alpha(Homo sapiens (Human))
Harvard Medical School
Curated by ChEMBL
Harvard Medical School
Curated by ChEMBL
Affinity DataEC50: 90nMAssay Description:Inhibition of PDGFRalpha by cellular assayMore data for this Ligand-Target Pair
Affinity DataEC50: 90nMAssay Description:Activation of caspase 3/7 in human 22Rv1 cells by Caspase-Glo reagent based analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 94nMAssay Description:Inhibition of HDAC in human HeLa cells using FLUOR DE LYS-SIRT1 as fluorogenic substrate incubated for 4 hrs by spectrophotometer based analysisMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 100nMAssay Description:Positive allosteric modulation of human GABAA alpha2beta1gamma2 receptor expressed in Xenopus laevis oocytes by two-microelectrode voltage-clamp assa...More data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Activation of Kir6.2/SUR1 (unknown origin) channel opening expressed in human T-REx-293 cells by thallium flux assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 125nMAssay Description:Inhibition of HDAC in human HeLa cells using FLUOR DE LYS-SIRT1 as fluorogenic substrate incubated for 4 hrs by spectrophotometer based analysisMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 138nMAssay Description:Inhibition of HDAC in human HeLa cells using FLUOR DE LYS-SIRT1 as fluorogenic substrate incubated for 4 hrs by spectrophotometer based analysisMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 150nMAssay Description:Activation of caspase 3/7 in human 22Rv1 cells by Caspase-Glo reagent based analysisMore data for this Ligand-Target Pair
Affinity DataEC50: 200nMAssay Description:Positive allosteric modulation of human GABAA alpha2beta1gamma2 receptor expressed in Xenopus laevis oocytes by two-microelectrode voltage-clamp assa...More data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 200nMAssay Description:Positive allosteric modulation of human GABAA alpha1beta2gamma2 receptor expressed in Xenopus laevis oocytes by two-microelectrode voltage-clamp assa...More data for this Ligand-Target Pair
Affinity DataEC50: 208nMAssay Description:Inhibition of HDAC in human HeLa cells using FLUOR DE LYS-SIRT1 as fluorogenic substrate incubated for 4 hrs by spectrophotometer based analysisMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 250nMAssay Description:Activation of Kir6.2/SUR1 (unknown origin) channel opening expressed in human T-REx-293 cells by thallium flux assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 310nMAssay Description:Activation of Kir6.2/SUR1 (unknown origin) channel opening expressed in human T-REx-293 cells by thallium flux assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 400nMAssay Description:Positive allosteric modulation of rat recombinant GABAA alpha6beta3gamma2 receptor expressed in Xenopus laevis oocytes assessed as increase in GABA-i...More data for this Ligand-Target Pair
Affinity DataEC50: 412nMAssay Description:Inhibition of HDAC in human HeLa cells using FLUOR DE LYS-SIRT1 as fluorogenic substrate incubated for 4 hrs by spectrophotometer based analysisMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 430nMAssay Description:Inhibition of HDAC in human HeLa cells using FLUOR DE LYS-SIRT1 as fluorogenic substrate incubated for 4 hrs by spectrophotometer based analysisMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 450nMAssay Description:Activation of human Kir6.2/SUR1 channel outward current expressed in HEK293 cells at -70 mV holding potential by EPC9 patch-clamp amplifier based ass...More data for this Ligand-Target Pair
Affinity DataEC50: 460nMAssay Description:Activation of Kir6.2/SUR1 (unknown origin) channel opening expressed in human T-REx-293 cells by thallium flux assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 530nMAssay Description:Activation of Kir6.2/SUR1 (unknown origin) channel opening expressed in human T-REx-293 cells by thallium flux assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 550nMAssay Description:Activation of Kir6.2/SUR1 (unknown origin) channel opening expressed in human T-REx-293 cells by thallium flux assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 560nMAssay Description:Activation of Kir6.2/SUR1 (unknown origin) channel opening expressed in human T-REx-293 cells by thallium flux assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 570nMAssay Description:Activation of Kir6.2/SUR1 (unknown origin) channel opening expressed in human T-REx-293 cells by thallium flux assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 610nMAssay Description:Inhibition of HDAC in human HeLa cells using FLUOR DE LYS-SIRT1 as fluorogenic substrate incubated for 4 hrs by spectrophotometer based analysisMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 660nMAssay Description:Activation of Kir6.2/SUR1 (unknown origin) channel opening expressed in human T-REx-293 cells by thallium flux assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 700nMAssay Description:Positive allosteric modulation of rat recombinant GABAA alpha6beta3alpha6-gamma2beta3 receptor expressed in Xenopus laevis oocytes assessed as increa...More data for this Ligand-Target Pair
Affinity DataEC50: 710nMAssay Description:Activation of Kir6.2/SUR1 (unknown origin) channel opening expressed in human T-REx-293 cells by thallium flux assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 710nMAssay Description:Activation of Kir6.2/SUR1 (unknown origin) channel opening expressed in human T-REx-293 cells by thallium flux assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 750nMAssay Description:Activation of Kir6.2/SUR1 (unknown origin) channel opening expressed in human T-REx-293 cells by thallium flux assayMore data for this Ligand-Target Pair
Affinity DataEC50: 780nMAssay Description:Activation of Kir6.2/SUR1 (unknown origin) channel opening expressed in human T-REx-293 cells by thallium flux assayMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 873nMAssay Description:Inhibition of HDAC in human HeLa cells using FLUOR DE LYS-SIRT1 as fluorogenic substrate incubated for 4 hrs by spectrophotometer based analysisMore data for this Ligand-Target Pair
Ligand Info
Affinity DataEC50: 880nMAssay Description:Activation of Kir6.2/SUR1 (unknown origin) channel opening expressed in human T-REx-293 cells by thallium flux assayMore data for this Ligand-Target Pair
Ligand Info